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3 edition of Phencyclidine and related arylcyclohexylamines found in the catalog.

Phencyclidine and related arylcyclohexylamines

Joint French-US Seminar on the Chemistry, Pharmacology, Present and Future of the Therapeutic Applications and Drug Abuse Aspects of Arylcyclohexylamines (1982 La Grande Motte, France)

Phencyclidine and related arylcyclohexylamines

present and future applications : proceedings of the Joint French-US Seminar on the Chemistry, Pharmacology, Present and Future of the Therapeutic Applications and Drug Abuse Aspects of Arylcyclohexylamines held in La Grande Motte (Montpellier), France, September 20-24, 1982

by Joint French-US Seminar on the Chemistry, Pharmacology, Present and Future of the Therapeutic Applications and Drug Abuse Aspects of Arylcyclohexylamines (1982 La Grande Motte, France)

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  • 13 Currently reading

Published by NPP Books in Ann Arbor, MI .
Written in English

    Subjects:
  • Phencyclidine -- Congresses.,
  • Phencyclidine -- Derivatives -- Congresses.

  • Edition Notes

    Statementeditors, Jean-Marc Kamenka, Edward F. Domino, Patrick Geneste ; copy editor, Antoinette F. Domino.
    ContributionsKamenka, Jean-Marc., Domino, Edward F., 1924-, Geneste, Patrick., Société de chimie thérapeutique (France), Centre national de la recherche scientifique (France), National Science Foundation (U.S.), France. Ministère de la défense. Direction des recherches, études et techniques.
    Classifications
    LC ClassificationsRM666.P49 J65 1982
    The Physical Object
    Paginationxxi, 690 p. :
    Number of Pages690
    ID Numbers
    Open LibraryOL3190505M
    ISBN 100916182045
    LC Control Number83061728

    Phencyclidine, commonly known as PCP, can be classified as an anesthetic, a dissociative, or a was originally dispensed as an anesthetic and as an animal tranquilizer, and during the s and 70s, it gained popularity as a recreational to its many side effects, PCP and its chemical precursor piperidine were made illegal in ; and its popularity waned over the. Media in category "Phencyclidine" The following 22 files are in this category, out of 22 total. 1-(1-phenylcyclohexyl) 1, × 1,; 14 KBHas part: nitrogen, carbon.

    Phencyclidine, more commonly known as PCP, was originally developed in the s as an intravenous anesthetic, but has been discontinued due to serious side effects. However, PCP is often sold on the illegal drug market in various forms and it can be mixed easily with dyes. Tablets, capsules and colored powder are the forms that [ ]. provides accurate and independent information on more t prescription drugs, over-the-counter medicines and natural products. This material is provided for educational purposes only and is not intended for medical advice, diagnosis or treatment. Data sources include IBM Watson Micromedex (updated 10 Apr ), Cerner Multum™ (updated 6 Apr ), Wolters Kluwer™ .

    phencyclidine hydrochloride: 1 n a drug used as an anesthetic by veterinarians; illicitly taken (originally in the form of powder or `dust') for its effects as a hallucinogen Synonyms: PCP, angel dust, phencyclidine Type of: hallucinogen, hallucinogenic drug, psychedelic drug, . @article{osti_, title = {Electroencephalographic, behavioral and receptor binding correlates of phencyclinoids in the rat}, author = {Mattia, A and Marquis, K L and Leccese, A P and el-Fakahany, E E and Moreton, J E}, abstractNote = {The pharmacology and structure-activity relationship of phencyclidine (PCP)-like drugs (phencyclinoids) were studied using electroencephalographic (EEG.


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Phencyclidine and related arylcyclohexylamines by Joint French-US Seminar on the Chemistry, Pharmacology, Present and Future of the Therapeutic Applications and Drug Abuse Aspects of Arylcyclohexylamines (1982 La Grande Motte, France) Download PDF EPUB FB2

92 rows  History. Phencyclidine (PCP) is believed to be the first arylcyclohexylamine with recognized anesthetic properties, but several arylcyclohexylamines were described before PCP in the scientific literature, beginning with PCA (1-phenylcyclohexanamine) the synthesis of which was first published in PCE was reported in and PCMo inwith the latter compound described as a potent.

Get this from a library. Phencyclidine and related arylcyclohexylamines: present and future applications: proceedings of the Joint French-US Seminar on the Chemistry, Pharmacology, Present and Future of the Therapeutic Applications and Drug Abuse Aspects of Arylcyclohexylamines held in La Grande Motte (Montpellier), France, SeptemberPhencyclidine, or PCP, chemically one of the arylcyclohexylamines, was originally developed as a dissociative anesthetic in the late s.

It was abandoned (for humans, but not other primates) in the mid s because patients so often showed marked confusion and irrational behavior mimicking schizophrenia during postoperative recovery.

Dept. of Human Services, 2 books Robert C. Petersen, 1 book Joint French-US Seminar on the Chemistry, Pharmacology, Present and Future of the Therapeutic Applications and Drug Abuse Aspects of Arylcyclohexylamines ( La Grande Motte, France), 1 book Harvey W. Feldman, 1 book Ronald L.

Linder, 1 book Jennifer Croft, 1 book Gerald Newman, 1. Phencyclidine (PCP), also known as angel dust among other names, is a drug used for its mind-altering effects.

PCP may cause hallucinations, distorted perceptions of sounds, and violent behavior. As a recreational drug, it is typically smoked, but may be taken by mouth, snorted, or injected.

It may also be mixed with cannabis or tobacco. Adverse effects may include seizures, coma, addiction Routes of administration: Smoking, injection. entific status of phencyclidine (PCP) and related arylcyclohexylamines.

The seminar was attended by 58 scientists interested in the chemistry, biochemistry, pharmacol- ogy, therapeutic applications and drug abuse aspects of arylcyclohexylamines.

Thirty-four American, 19 French, 3 Japan ese, 1 British and 1 Israeli investigator. First discovered in5 unlike related compounds such as ketamine and PCP, BTPC “lacks any anticonvulsant, anesthetic, hallucinogenic, or dissociative effects”, due to negligible affinity for the NMDA receptor, 6 instead acting as a potent and selective dopamine reuptake inhibitor (DRI), 7 and as a psychostimulant.

Wolfe SA Jr, De Souza EB. Sigma and phencyclidine receptors in the brain-endocrine-immune axis. NIDA Res Monogr ; Cook CE, Brine DR, Quin GD, et al. Phencyclidine and phenylcyclohexene disposition after smoking phencyclidine.

Clin Pharmacol Ther ; Aronow R, Done AK. Phencyclidine overdose: an emerging concept of management. Vaupel DB () Phencyclidine studies in the dog. Pharmacology of PCP, profiles of eight analogues abused by man and the similarity of PCP to the opioid NANM (N-allylnormetazocine or ).

In: Domino EF (ed) Phencyclidine and related arylcyclohexylamines: present and future applications. NPP Books, Ann Arbor, pp – Google ScholarCited by: 7.

Phencyclidine is a member of the class of piperidines that is piperidine in which the nitrogen is substituted with a 1-phenylcyclohexyl group. Formerly used as an anaesthetic agent, it exhibits both hallucinogenic and neurotoxic effects.

It has a role as a neurotoxin, a psychotropic drug, an anaesthetic and a NMDA receptor antagonist. It is a. Kamenka JM, Domino EF, Geneste P. Phencyclidine and Related Arylcyclohexylamines: Present and Future Applications. Ann Arbor, MI: NPP Books; Kashiwagi K, Masuko T, Nguyen CD, Kuno T, Tanaka I, Igarashi K, et al.

Channel blockers acting at N-methyl-D-aspartate receptors: differential effects of mutations in the vestibule and ion channel by: Methoxetamine (MXE) is a new synthetic drug of abuse structurally related to ketamine and phencyclidine. A case of a year-old male with acute toxicity related to the analytically confirmed use.

The substance-related disorders encompass 10 separate classes of drugs: alcohol; caffeine; cannabis; hallucinogens (with separate categories for phencyclidine [or similarly acting arylcyclohexylamines] and other hallucinogens); inhalants; opioids; sedatives, hypnotics, and anxiolytics; stimulants (amphetamine-type substances, cocaine, and other stimulants); tobacco; and other (or unknown.

In this Perspective, Vollenweider and Kometer discuss the clinical potential of psychedelic drugs for the treatment of various psychiatric disorders, and describe the molecular mechanisms by which Cited by: Phencyclidine definition is - a piperidine derivative C17H25N used chiefly in the form of its hydrochloride especially as a veterinary anesthetic and sometimes illicitly as.

Author(s): Kamenka,Jean-Marc; Domino,Edward F,; Geneste,Patrick; Joint French-US Seminar on the Chemistry, Pharmacology, Present and Future of the Therapeutic Applications and Drug Abuse Aspects of Arylcyclohexylamines,( La Grande Motte, France) Title(s): Phencyclidine and related arylcyclohexylamines: present and future applications: proceedings of the Joint French-US Seminar.

PheneYclidine pharmacokinetics and concentration-response relationships in the pigeon. PHARMACOL BIOCHEM BEHAV 35(4)-Phencyclidine (PCP) phatmacokinetics and drug discrimination were examined in pigeons (n=6 in both groups) after intramuscular doses of mg/: S.

Michael Owens, D.E. McMillan, William C. Hardwick, William D. Wessinger. The published preparations of PCP and its analogs may be considered in three groups: those which employ the nitrile (2), those which depend upon the formation of a Schiffs' base as an intermediate, and those which invoke an enamine most important and most frequently used route to PCP and to its analogs which maintain a cyclic amine function, exploit the facile displacement of the.

Volumenumber 1 FEBS September Phencyclidine (PCP) blocks glutamate-activated postsynaptic currents M. Idriss and E.X. Albuquerque* Department of Pharmacology and Experimental Therapeutics, University of Maryland School of Medicine, W.

Redwood Street, Baltimore, MDUSA Received 9 July Phencyclidine (PCP) was tested on the metathoracic tibialis muscles of Cited by: The solution to crime inwith over 70 percent of criminals is drugs and alcohol related, forcing our society to see the correlation of people who commit crime and are substance abusers and not really criminals at heart will cause the necessary change required to benefit society as a whole.

Ketamine-related – The Arylcyclohexylamines Author Will Phuq Date 28 November Ketamine numbers many relatives in the arylcyclohexylamine class (of which it is itself a.Structure of PCP Analogs.

PCP (phencyclidine, or 1-phenyl-cyclohexylpiperidine (figure 1, below) is the best known representative of the class of drugs collectively known as arylcyclohexylamines.

Two other members of this structural class are ketamine and tiletamine. PCP was formerly used as a surgical anesthetic in both humans and veterinary.^Maisto, Stephen A.; Mark Galizio, Gerard Joseph Connors (). Drug Use and on Wadsworth. ISBN ^ Development of PCP, ,CESAR (Center for Substance Abuse Research) ^ Drugs and Behavior, 4th Edition, McKim, William A., ISBN ^ Kapur, S.

and P. Seeman. "NMDA receptor antagonists ketamine and PCP have direct effects on the dopamine D2 and CAS number: